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The Combined Oral Contraceptive Pill Versus Bromocriptine to Suppress Lactation in Puerperium : A Randomized Double Blind Study


Worapitaksanond MA*, Kitinan Sittichai BA*,
Porndara Saechua BA*, Anantaporn Nomrak BA*
* Department of Obstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University


A randomised double blind comparative study of 230 HIV infected mothers who had a normal
delivery at 37-42 weeks’ gestation were divided into two groups; 116 combined pill users and 114
bromocriptine users to suppress lactation. There were 33 cases (28.5%) of combined pills users and 29 cases
(25.4%) of bromocriptine users who had breast engorgement without statistical difference. All of them had
mild breast engorgement without any treatment except one case (0.9%) in the bromocriptine group had
severe breast engorgement with puerperal fever and needed an analgesic drug. There were no side effects of
the drugs. This study showed that combined pills were beneficial to suppress lactation in HIV infected
mothers to prevent postnatal mother-to-child transmission because of low risk and low cost.

Keyword : Suppress lactation, Combined pills, Bromocriptine, HIV infected mother, Breast engorgement

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