Proundly Supported by
Pfizer Foundation
    Home | Current Issue | Past Issue | Board | Instruction | Contact

Device-Associated Infections and Patterns of Antimicrobial Resistance in a Medical-Surgical Intensive Care Unit in a University Hospital in Thailand


Somchit Thongpiyapoom RN*, Montha Na Narong RN*,
Nonglak Suwalak RN, MPA*, Silom Jamulitrat MD**,
Prasopsuk Intaraksa RN*, Jaruwan Boonrat RN*,
Nongyao Kasatpibal RN, MNS***, Akeu Unahalekhaka RN, MSc***
* Songklanagarind Hospital
** Department of Community Medicine, Faculty of Medicine, Prince of Songkla University
*** Faculty of Nursing, Chiang Mai University


Background : Surveillance of nosocomial infection in the intensive care unit (ICU) received a high level of attention and outcome indicators are now used in benchmarking the quality of patient care. Since 1999 the surveillance has targeted three site-specific, device-associated infections, including ventilator-associated pneumonia (VAP), central-line-related bloodstream infection (CR-BSI), and catheter-related urinary tract infection (CR-UTI). The authors conducted a two-year prospective study on the incidences of these infections acquired in an ICU and report herein, together with the antibiotic susceptibility patterns of the microorganisms isolated in an ICU.
Patients and Method : Continuous prospective data collection was conducted on patients admitted to an adult medical-surgical ICU of a university hospital in Thailand from June 2000 to May 2002.
Results : A total 1422 patients with a total of 9370 patient-days were enrolled in the study. The incidence of VAP, CR-BSI, and CR-UTI were 10.8/1000 ventilator-days (95%C.I: 8.5-13.6), 2.6/1000 central-line-days (95%C.I: 1.5-4.4), and 13.8/1000 urinary-catheter-days (95%C.I: 10.7-17.5) respectively. The most common causative pathogens were Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae. The proportion of methicillin-resistant Staphylococcus aureus, imipenem-resistant P. aeruginosa, ceftazidime-resistant A. baumannii, third-generation-cephalosporin-resistant K. pneumoniae, and quinolone-resistant E. coli were 68.8%, 30.9%, 68.5%, 44.6%, 38.3% respectively.
Conclusion : The incidences of VAP and CR-BSI were comparable to the National Nosocomial Infection Surveillance (NNIS) report. But the incidence of CR-UTI was over the 90th percentile. The antibiotic resistance had become a serious problem.

Keyword : Intensive care unit, Cross infection, Device-associated infection, Antimicrobial resistance

Download Full Paper
  Vol87_No7_819.pdf  [ 77.91 Kb]

Home | Current Issue | Past Issue | Board | Instruction | Contact

© Copyright The Medical Association of Thailand. All Rights Reserved.2001-2002
Acquista Cialis generico 5 mg Effetti collaterali del Cialis 5 mg Acquista Cialis 20mg online Prezzo di Cialis originale in Svizzera Acquista Viagra in Svizzera senza prescrizione Dove comprare Cialis 10mg Viagra in farmacia online effetti collaterali Costo di Cialis 5mg Opiniones de Reduslim Acquista Spedra Avanafil senza prescrizione Acquista Viagra in Svizzera senza prescrizione Comprar Cialis original Comprar Viagra Contrareembolso Cialis 5mg Viagra sin receta Cialis 5 mg efectos secundarios graves Reduslim precio Trastorno de la ereccin venta de tadalafilo avanafil prezzo cialis 20 mg prezzo cialis effetti benefici cialis 10 mg Reduslim Kaufen pulse crypto price prediction avanafil 100 mg prezzo